As we see the progress of the divine promise through the line of Jacob, we also see that Esau married into Ishmael's side of the family (Genesis 28:8-9). The tremendous experience, given by God to Jacob (Genesis 28:10-22) was one of the great turning-points in Jacob's life (see also Genesis 32:22-23). It was on that night that he became a new man. The story of Jacob became a story of blessing, a story of a man being led by the Lord Himself on "a stairway ... reaching to heaven" (Genesis 28:12).
Jesus said, "Blessed is anyone who does not stumble on account of Me" (Matthew 11:6). The story of Esau became a story of an increasing falling away from the Lord. The story of God's enemies is summed up in Psalm 9:3 - "My enemies turn back; they stumble and perish before You."
The testimony of the saved is summed up in Psalm 9:1-2 - "I will give thanks to you, Lord, with all my heart; I will tell of all Your wonderful deeds. I will be glad and rejoice in You; I will sing the praises of Your name, O Most High."